You might have friends who debate the merits of eastern medicine versus western medicine. Modern sciences stacked up against thousands of years of natural remedies. While both sides carry multitudes of legitimate arguments, it's possible both sides would agree that all of the below treatments are a little out there.
Reddit user, u/1234byfeist, wanted to know:
Check. Double Check. Check Fifteen More Times.
It was many years ago and I was working with end-stage cancer patients. This one woman, who began her treatment outside of the United States, was given a mixture of cocaine, heroin, alcohol, morphine, phenothyazine and some other antiemetics. It was specially made into a liquid and imported from somewhere in Europe. I remember this med so vividly because it's not everyday you give someone heroin. I think it was called something like Bromton Cocktail and the lengths that were gone to to check out and administer a dose of that stuff - we're talking who's got the nuclear codes type of system. I have to admit though, it worked like magic.
The Costs Add Up Over A Year
The rarest medication I have administered is eculizumab (Soliris) which is used for PNH. A single dose costs around $20,000 and it is administered every two weeks at a cost of around $540 000 per year. It is delivered by armoured courier and the patients do get a 24h concierge they can always contact.
The patient told me it was expensive, and being aware of very expensive biologics I told her, "Yes, many of the new monoclonal antibodies are very expensive and can cost up to $20 000 per year."
She corrected me, that it cost $20 000 per dose. I didn't believe her but while organizing the infusion I figured I better read up on a drug I was administering for the first time and, yup, $20 000 a dose--26 doses a year--for the rest of her life.
Aquamans_DadSpeak Your Truth To Yourself
Sodium thiopental-truth serum.
In residency, someone had a conversion disorder in a movie theater (I know, way back when it was a normal thing to do). The entire place cleared out after the movie, his buddies are talking and realize he's not getting up. He finally tells them he is paralyzed and can't move.
Medics brought him in, he's laying in the gurney in the sitting position, like he's an astronaut. I walk in the room and think to myself, whaaat the f---ck. I go ahead and take his history, go back and present him to my attending. Attending asks me what I want to do. I'm at a serious loss here, I have no f-cking clue other than wait him out, nobody's core is that strong. He says we should give him thiopental.
Of course I say lets do it. We go in with just us and a nurse, he turns the lights off, the nurse pushes the meds. My attending proceeds to walk this guy down with confidence and empathy, like he's walking him through the worst lsd trip ever.
Sure enough, my attending asks him to realize that his arm is attached to his chest which is attached to his back which connects to his neck which connects to his brain. He tells the guy, now is the time to move your arm. The kid moves his f-cking arm! AMAZING. After a bit longer the kid is lying flat. Soon enough he's up a moving. Craziest sh-t I saw that year. Emergency medicine, still not dull 10 years later.
spewgeneCarefully...CAREFULLY!
Activated protein c. Can't remember exactly but it was about £50k a dose. Used in severe last ditch sepsis treatment. Not a vial you want to drop.
Artificial Body Parts
It's been a few years so I might butcher the name... Alpha-1 antitrypsin proteinase inhibitor? I've only given it to two patients but they had to get it regularly. It's a synthetic version of a protein, I think, that is made in the liver and usually inhibits the action of a particular enzyme in the lungs that breaks down tissue to ensure that dead cells don't interfere with lung function or something like that.
But in these patients, either the protein was being made wrong in such a way that it couldn't pass through the bile duct and escape the liver, or it just wasn't being made. Without an inhibitor, the enzyme just keeps breaking down tissue, and that causes emphysema. These patients had to get this medication once a week, for the entirety of their lives, but they're the only patients I ever heard of that needed it.
I was only a Hospital Corpsman in the Navy at the time, not even a licensed nurse; I only have a surface understanding of what exactly was going on, so sorry if I got anything wrong in the explanation. This was administered in an ambulatory infusion clinic at a naval hospital; I administered it and had to understand it to anticipate any potential side effects and double check dosing and rate but an actual doctor created the treatment plan and everything.
Space Age Medicine
Methylene blue. I gave it to a girl who tried overdosing on Orajel. The active ingredient is benzocaine which caused her to develop a methemoglobinemia, treated with the blue drug. It truly is an artificial looking bright blue and I gave it to her in her IV.
Redirect That Blood Flow
Viagra for patient with pulmonary hypertension, only serve it once.
Other than that, thalidomide for anti nausea which is very rare and anti venom for snake bite.
GOOD. LORD.
Luxturna.
One dose per eye, USD $425,000.00 per eye.
THE MOST EXPENSIVE TREATMENT IN THE WORLD.
What does it treat?
The answer to tour question is very technical, but here it goes.
LUXTURNA is for individuals with an inherited retinal disease caused by mutations in both copies of the RPE65 gene and who have enough remaining cells in the retina
A gene is the basic unit of hereditary information that is passed on to a child from their parents. Typically, every person has 2 copies of a gene, one from each parent. In the case of RPE65 gene mutations, both of the genes passed onto the child were mutated.
There are many inherited retinal diseases
For example, Leber congenital amaurosis and retinitis pigmentosa are two inherited retinal diseases. These are clinical diagnoses that are not based on mutations in specific genes, such as mutations in both copies of the RPE65 gene. To get a genetic diagnosis, you will need a genetic test.
LUXTURNA is a one-time gene therapy for each eye
Gene therapy is a method for treating a genetic disease. One approach to gene therapy is delivering a new or functional gene into a cell.
LUXTURNA works to restore the visual cycle.
The visual cycle is a process that allows you to see. LUXTURNA provides a working RPE65 gene to act in place of a mutated RPE65 gene. This working gene has the potential to make the visual cycle work properly again.
So, There's A Wrong Way To Take This?
I had a woman who was on Ziconotide, which is an analgesic derived from Cone Snail venom. If it isn't administered correctly (through the spine), it causes hallucinations.
Wait, Seriously?
Pharmacist here and leeches. We use them to keep blood flowing if you get a finger or ear or something cut off and sewn back on.
Nope. Too Much. Leaving.
Maggots. We had a drug addict come in who had let an infection go so long in his arm from repeated needle usage that all our attempts to clean it failed. We ended up using maggots to eat away the dead tissue, while leaving the healthy tissue intact. Dude just had an open wound full of maggots loosely covered in some gauze for like... several days.
The worst part is always having to collect them afterward.
The medication most people are shocked by is cocaine hydrochloride. Yep. Cocaine. It's a good vasoconstriction agent, and topical anesthetic.
Everyone, You Know The Words To "We Didn't Start The Fire!"
In 15 years of hospital pharmacy, I've twice had occasion to dispense Thalidomide. It's used as an end-stage anti-nausea med, and comes very carefully packed, with all sorts of warnings about not coming near it if pregnant, and even has little pictures of Thalidomide babies.
...WaiBuWhat?
A poop/fecal transplantation. At my first internship during nursing school, there was a patient with a bowel infection caused by clostridium difficile. A few months before he got treated with broad-spectrum antibiotics for a pneumonia, which caused the infection. They tried other treatments to cure the infection, but nothing worked. Eventually, the patient got accepted in a clinic trial for a fecal transplant. One of his kids was the poop donor. After the transplantation the infection actually cleared up!
Getting Crunk In The ER
Vodka, because of methanol poisoning.
I was going to say the most surprising thing I saw in the fridge in the med room was a can of beer. Labeled (prn qd) and chilled for the patient.
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I would love to know how people don't fear death.
I mean, it's the end. Life will be over. That kind of sucks.
Yet there are people who find tranquility in it.
Can you teach the rest of us?
Redditor deensuk wanted to hear from everyone who has a calmness about the heading to the afterlife. They asked:
"People who are not scared of death, why?"
I have a constant fear of death. I wanna perfect the ending of "Death Becomes Her" so I can live forever.
Before
"I'm not scared of death because of working in health care I was around it so much. I AM scared of what leads to death, however."
Full-Mulberry5020
Why now?
"Why should I be scared now of something that's only going to happen at the end of my life?"
User Deleted
"I did this cult thing called the landmark forum and I actually did like their “meaning of life”: the meaning of life is that there is no meaning. Life is empty and meaningless. There is no answer."
"Life is what you make of it and every persons answer is equally valid because there is no meaning to life. Life exists as, basically, an accident, we are all here by complete accident, there’s no great mystery, it’s all biology and you are 100% free to make life about whatever it is you want."
Conservative_HalfWit
Death and I are good friends...
"I was very sick as a child. Spent ages 7-20 in and out of hospital due to kidney issues. Lost a kidney at 28. Almost died during the surgery to removed the dead kidney due to blood loss. Had 5 surgeries back to back during the next 2 years. Twice they had difficulties bringing me out of anesthesia."
"Found my favorite aunt dead in her bed when I was 22. Watched my best friend die from a brain tumor at 30. Death has been a constant force in my life. Sometimes just on the edges waiting, sometimes unexpected staring me in the face. I'm not afraid because it's always been there. I now work in healthcare. Death and I are good friends."
Tiny_Teach_5466
No Worries
"Because it's coming for us all, sooner or later. So there's no point in worrying about it. I am much more concerned about day to day minutiae. The Lars von Trier film Melancholia starring Kirstin Dunst portrayed this perfectly. If there was an asteroid hurtling towards the earth, I'd probably be more preoccupied with worrying about whether I left the back light on or not."
Giallo_submarine
It's Over
"Because no one has ever made it out alive, and I was dead for an eternity before I was alive, and didn't suffer the slightest inconvenience because of it."
MarshallApplewhiteDo
I never thought about the before much. I hope the before is quick.
The Effects
"I hope that when my times comes it will be merciful. My uncle had a stroke, he is paralyzed. My grandmother is 91, but is losing all her memories of her life. Death does not scare me, what could be left of me before I die is what terrifies me."
M1ssy_M3
No Terror
"It’s like when the writer Nabokov said that he saw a picture one time, a picture of before he was born. It was a picture of his mother, his brother and sister that were older than him, but he had not been born yet. He said that when he saw that picture there was no terror in him, even though he was looking at a picture where he didn’t exist."
im_on-the_can
state of nonexistence...
"I'm not afraid of death, I'm afraid of dying. Death is just the state of nonexistence I experienced before I was born. I don't remember it because I didn't exist yet. Death will be the same way. I just don't want the transition to be marked by pain and sorrow at things left unfinished. I want it to be quick, painless, and with me surrounded by love."
Wazula42
I'm Gone...
"Because once I die, I won't know it. I won't miss people or regret things or feel pain or sadness about anything. I might fear being sick and slowly dying, just having to live with the knowledge that it's all going to end and this is the last time I'll ever see the people I love or taste good food or hear good music. That sounds almost unbearable. But death isn't even a thing, it's just having done something (died)."
"It's like virginity, it's a made-up state of being that just says whether or not you've experienced a specific occurrence. Once I die, I'm gone. My corpse will be the empty wrapper I used to be in, just garbage to be disposed of in whatever way makes my survivors feel better. I'll be switched off. If I don't worry about what the light feels after the bulb burns out, why would I be afraid of being dead?"
SallyHeap
At Peace
"I’m scared now because I have young kids. Once my kids are old enough to be on their own I imagine the fear will subside and I’ll have a more relaxed approach."
User Deleted
Some very interesting perspectives. May it all calm peacefully and with great mercy for us all.
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Dating and the search for love and companionship... What a nightmare.
This journey plays out nothing like in the movies.
Every Prince or Princess (or everything in BTW) seems to have a touch of the psycho.
The things people say during what should be simple dinner conversation can leave a dining partner aghast.
Like... do you hear you?
Redditor detroit_michigldan wanted to discuss all the best ways to crash and burn when trying to make a romantic connection. They asked:
"You're on a date and it's going really great. What can another person say to ruin it completely?"
I once had a guy ask me if I was willing to follow him into the woods, depending on the price of the meal.
Yeah. No steak is worth that.
Plans After...
"Thanks for the ride but I have a date with someone else, I figured you wouldn't drive me if you knew I was going on a date with someone else and I really needed a ride."
"Online dating, talked to her for a while, finally got the courage to ask her out and then she said that as we got there."
iareyours
Mirror Image
“'You look just like my wife!'”
catalinachild
"I did have a guy tell me I reminded him of his son. I don’t believe English has a word to adequately describe my feelings at that time."
UnicornMagicRainbow
"That would definitely do it."
chaotica78
Third Wheel
"'Hope you don't mind if my mother joins us.'"
ofsquire
"Actually had a girl do this on a first date because she had anxiety issues. Honestly wasn’t bad except that 90% of the time she was silent and her mom talked over her."
"I didn’t mind that much and wouldn’t have minded trying again when she was more comfortable except that she was let go at the company we worked at and she deleted her social media profiles and she never responded on her number. Ah well."
Seightx
Liar
"'Hey bro aren't you gay? I made out with you last night.'"
"Random dude I've never seen before in front of my (f) date."
JHXC16
Was he lying though?
Filter Issues
"'You looked better on Tinder.'"
waqasnaseem07
"Isn’t it basic knowledge that everybody looks slightly worse than the worst picture you can find?"
no_user_ID_found
The Past
"'My ex used to do that too.'"
xxIvyOF
"Yep. I’ve definitely had two otherwise-decent-guy date-situations sour because the ex-comparisons just would not stop flowing. No woman wants to be seen as interchangeable—I’m not here to perfectly fill that ex-sized hole in your life. Focusing on the present moment and a future we could build together is a courtesy we need to grant each other in earliest dates of dating."
LarkScarlett
Powerless
"'I'm an alpha, you cant handle my top energy.'"
Midnightgay28
"I actually left a dude in the middle of dinner, in part, for saying this. I ordered an Uber under the table while pretending to listen to him. Went to the bathroom, and never came back. That was when I was young. Now I’d just say, 'How about we enjoy this meal in silence, before we head our separate ways.'”
UnicornMagicRainbow
Mommy...
"'Mother says I should be back by 9.'"
"Saying 'mother says' just feels weird."
bunnyrut
"That gives me Norman Bates vibes."
Werewolf_lover20
"'Mother says alligators are aggressive because they have an overabundance of teeth, but lack a toothbrush.'"
sodaextraiceplease
Obvs...
"'If you were going to be murdered, what method would you prefer. Purely hypothetical. Obvs.'"
Specific_Tap7296
If it looks anything like a Dateline NBC episode... RUN!
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Despite the advancement of technology rendering people left to their own devices–literally–to entertain them, there are some leisurely activities that will never go out of style.
Or so you would think.
Do people still knit to pass the time? Are people actively collecting stamps?
It depends on who's asking.
Curious to hear about hobby trends, Redditor gizehgizeh asked:
"What are once popular hobbies that are slowly dying these days?"

Before we've become conditioned to living on our phones, these activities used to keep people occupied.
Before Texting, There Was This
"Letter writing."
– littlekingMT
Literal And Tangible Joy
"Well the internet killed pen pals for sure. I do remember I had a Japanese girl for a penpal maybe back in 2007 or so. I honestly don't remember how it started, pretty sure some website, but that was a fun experience. But now I can just straight up talk to foreign people real time, lol. But yea getting a physical letter that someone took the time to write and mail still is hard to beat feelings wise."
– skyburnsred
Model Trains
"When I was growing up, every town had a model train store in it. Now I have one in region and everything else has to be bought online."
– Hairy_Effective1172
Pretty Rocks
"Don’t see anyone playing marbles anymore, I had an awesome collection in school."
– sheeple85
"I had some marbles as a kid in the 90s. My grandma got them for me and I had no idea what I was supposed to do with them. I always imagined them as a thing kids in the 40s played with."
– Ryoukugan
People Were Moving Canvases
"Paintball has been dying a slow death since 2006. Sad, really."
– hobo_recycler
Before the general population began hating clutter, collecting was once a "thing."
Precious Coins
"Coin collecting... I'm a silver/gold nut and I'm always hunting for precious metal coins. whenever I go into a shop they get all excited because 'no one under 70 collects coins anymore.'"
– ThatFishySmell99
Post It
"Stamp collecting."
– spooky_scully_mulder
"Collecting in general, really. Of course there are still prominent collectors but it's slipped more into enthusiast and niche territory than being a popular hobby that you might expect anyone to have."
– iuytrefdgh436yujhe2
What A Gem
"Rockhounding was immensely popular back in the 1950's and 1960's. Personally, I think it's a fascinating and fulfilling hobby, but when I go to a meeting at a rock and gem club, I'm usually the youngest one in the room by several decades."
– filthy_lucre
People once enjoyed making things.
Admiring The View
"Stained glass. I learned how to make it from my old man, and my junior high art class teacher also taught it. Very few artisans are still around."
– brobeanzhitler
Metal Vocation
"Black smithing."
– kenworth117
"I bought a forge to try. It’s insanely hard work, and crazy expensive. I still haven’t finished a piece."
– DSentvalue
Scrapbooking
"Yeah. I'm watching the arts and crafts stores around me completely uninstalling their racks for specialty paper. Now the only thing they have is mega packs of repeating colors/images. To boot all the inclusions like papercraft/die-cut things, washi tape, scissors, stickers, etc have gotten so expensive I would rather go buy $5 bags at value village to get an assortment of things versus buying anything new. I really, really miss yard sales for the same reasons."
– Phantasmai
I envy people who have jobs that are basically their hobbies.
Not everyone gets paid doing what they actually enjoy and have a profound level of passion for.
If they do, kudos to them.
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When we first meet someone–whether through mutual friends, at school, or in a new work setting–we generally feel people out to determine if they're worth getting to know.
While the process could take time, some people make our jobs much easier after spotting instant red flags.
Curious to hear about our general radar of people, Redditor xxFluffie asked:
"What is something that makes you immediately dislike someone?"

Some people just think they are absolutely hilarious and never realize they're the only ones laughing.
Next In Line
"They laugh about having screwed someone else over. If you think you're not next, well, you'll learn."
– whiznat
Unfunny
"when you mention you don't like a thing and they immediately do that thing 'as a joke.'"
– wayfinder
Playing Devil's Advocate
"Kneejerk contrarians. People who, no matter what you say you like or believe, just have to dismiss it and say they like or think the opposite."
– BubbhaJebus
People who put others down get slammed here.
Bad Parents
"When they treat their kids sh**ty in public. I don't mean handling tantrums, setting a rule, having to hurry to the train etc. I mean perfectly normal-behaved kids getting in trouble for trailing along peacefully, looking at things, asking questions etc."
"If you don't like tiny humans who learn the world, why have them??"
– raxeira-etterath
Public Humiliation
"Treating people sh**ty in public for laughs. Like being rude to service workers because they think it’s funny. Big red flag."
– Ok_Personality_1080
Simply Uncalled For
"Someone who is a d*ck to other people or animals for no reason."
– xebt1000
Those with ulterior motives rubs people the wrong way.
The Scheme
"If they try to get me to join their MLM scheme."
– spazmcgee1
Hard Sell
"A guy I used to be friends with in high school reached out a couple of years after graduating about a business opportunity he wanted my opinion on because 'you've always been smart', then he set up a Skype call and brought some other dude into the call and they started trying to sell me on what was clearly an MLM scheme. The guy went from friend to 'I'm never talking to you again' in a matter of 10 minutes."
– Mental-Afternoon-164
A Timeline
"Good gawd, this! I've had more than one exposure to this abject bullsh**tery..."
- Back in the late 80's/early 90's I was invited to a meeting of literally the OG "Pyramid" where you're recruited to pay in, and then you go out and recruit others to pay in, and the last in line got f'kall.
- In 1995 I had a coworker try to reel me into Amway, which was a hard no.
- In 2000 it was Pampered Chef, though to be fair they did have useful products.
- In 2009 a coworker tried to get me into some stupid video calling service that was obviously stupid from the description. He even got offended when I called bullsh*t.
– Mystical_Cat
Too much ego is a no-go.
I Can Do Better
"Being a b*tch just to stroke their own ego."
"We get it, you can lift 5lbs more than the 12 year old, you don't have to rub it in their face just because you're slightly better"
– Livia_Pivia
Can't Top This
"Oh, you did <story that's been told>? That's nothing! I did <implausible story>.
"I get the whole empathy through relating common experience, and I'm someone who does that (which drives some people crazy on its own), but there's a big different by empathising through common experience, and one-upmanship."
– Tisarwat
Lacking Conversational Etiquette
"Starting to talk over me when I was already talking."
"Stop it you rude, arrogant jerk."
– R33Gtst
If one or more of these traits sound familiar to you, you're not alone.
We don't have time for braggadocios, pyramid-schemers, and conversation interrupters.
And that's just for starters.
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